Formation Response of High Frequency Electromagnetic Waves

Core samples from rock formations respond to electromagnetic radiation based on an effective permittivity, which depends on the conductivity and permittivity of the constituent components of the rock, as well as the geometric structure of these constituents and the frequency of the radiation. This study analyzes the effect, for radiation of 1 to 100 Mhz, of discrete inclusions having a different permittivity from the surrounding medium. The focus is on the effect of certain geometric features, namely, the individual size of the inclusions, their overall volume fraction, the presence of sharp edges, and their aspect ratio. It is found that the volume fraction has the strongest impact on the effective permittivity, linear at first but higher order at higher volume fractions. The aspect ratio of the inclusions has a moderate effect, which is exaggerated in the extreme case of needle-like inclusions, and which can also be seen in a stronger nonlinearity. There is also a possibility that some features in the shape of the inclusion boundaries may influence the frequency dependence of the effective permittivity. Inclusion size and sharp edges have negligible effect

Spectral algorithms for reaction-diffusion equations

A collection of codes (in MATLAB & Fortran 77), and examples, for solving reaction-diffusion equations in one and two space dimensions is presented. In areas of the mathematical community spectral methods are used to remove the stiffness associated with the diffusive terms in a reaction-diffusion model allowing explicit high order timestepping to be used. This is particularly valuable for two (and higher) space dimension problems. Our aim here is to provide codes, together with examples, to allow practioners to easily utilize, understand and implement these ideas; we incorporate recent theoretical advances such as exponential time differencing methods and provide timings and error comparisons with other more standard approaches. The examples are chosen from the literature to illustrate points and queries that naturally arise

Analysis of surface atrial signals using spectral methods for time series with missing data

In this work, the analysis of atrial signals recorded during atrial fibrillation was pursued using two spectral estimators designed for series with missing data: the Lomb periodogram (LP) and the Iterative Singular Spectrum Analysis (ISSA). The main aim is to verify if subtraction ofthe ventricular activity might be avoided by performing spectral analysis on those ECG intervals where such activity is absent, (i.e. the T-Q intervals), at least to estimate the dominant atrial Fibrillatory Frequency (FF). Recordings coming from the 2004 Computers in Cardiology Termination Challenge Database were analyzed. Fibrillatory frequencies were then compared with those obtained from the analysis ofthe correspondent atrial signals extracted using a modified Average Beat Substraction (ABS) technique. We observed that the mean absolute difference was 0.42 \ub1 0.66 Hz for LP, (mean\ub1SD), and 0.39 \ub1 0.64 Hz for ISSA. We concluded that estimation of FF is feasible without applying QRS-T subtraction

Cancellation of ventricular activity in endocavitary recordings during atrial fibrillation by Particle Swarm Optimization

The cancellation of ventricular activity (VA) from atrial electrogram (AEG) is commonly performed by template matching and subtraction (TMS): a running template, built by adaptive averaging of AEG segments in correspondence of QRS, is subtracted from AEG to uncover atrial activity (AA). In our approach, before subtraction, templates are modulated by a set of coefficients which are estimated by maximizing, via Multiple Particle Swarm Optimization (MPSO), a fitness function based on: 1) the energy of the estimated and measured AA; 2) the first derivative of the estimated and measured AA; 3) the similarity between the template and its modulated version. To validate the method, three datasets of 500 synthetic AEG were built. Each signal included background AA, localized AA and VA. We observed that TMS+MPSO provided better performances then TMS alone when the ratio of VA/AA amplitude is large (VA/AA 65 3), while the performances get closer when the ratio decreases

Assessment of spatial heterogeneity of ventricular repolarization after multi-channel blocker drugs in healthy subjects

Background and objectives: In contrast to potassium channel blockers, drugs affecting multiple channels seem to reduce torsadogenic risks. However, their effect on spatial heterogeneity of ventricular repolarization (SHVR) is still matter of investigation. Aim of this work is to assess the effect of four drugs blocking the human ether-\ue0-go-go-related gene (hERG) potassium channel, alone or in combination with other ionic channel blocks, on SHVR, as estimated by the V-index on short triplicate 10 s ECG. Methods: The V-index is an estimate of the standard deviation of the repolarization times of the myocytes across the entire myocardium, obtained from multi-lead surface electrocardiograms. Twenty-two healthy subjects received a pure hERG potassium channel blocker (dofetilide) and 3 other drugs with additional varying degrees of sodium and calcium (L-type) channel block (quinidine, ranolazine, and verapamil), as well as placebo. A one-way repeated-measures Friedman test was performed to compare the V-index over time. Results: Computer simulations and Bland-Altman analysis supported the reliability of the estimates of V-index on triplicate 10 s ECG. Ranolazine, verapamil and placebo did not affect the V-index. On the contrary, after quinidine and dofetilide administration, an increase of V-index from predose to its peak value was observed (\u394\u394V-index values were 19 ms and 27 ms, respectively, p < 0.05). Conclusions: High torsadogenic drugs (dofetilide and quinidine) affected significantly the SHVR, as quantified by the V-index. The metric has therefore a potential in assessing drug arrhythmogenicity

Self-reported knee symptoms assessed by KOOS questionnaire in downhill runners (skyrunners)

Background: The knee is the weight-bearing joint most commonly associated with sports injuries, and therefore is most at risk of developing degenerative changes, including osteoarthritis. Skyrunners can be considered to be at risk of developing symptoms of post-traumatic osteoarthritis due to downhill running. Aim: The aim of this study was to analyze the health of the knee joints of a large group of these athletes via a specific self-report questionnaire. Methods: This study was carried out by asking the participants of seven official Skyraces (22.4±3.1 km length; 1596±393 m elevation) to fill out a questionnaire. Information regarding age, sex, downhill elevation (m) during training and competitions over the last month, and history of previous knee injury was also collected before the participants filled out the Knee injury and Osteoarthritis Outcome Score (KOOS), which is a reliable and validated instrument designed to assess patients' opinions about their knees and associated problems that can result in post-traumatic osteoarthritis. Athletes were divided into six age groups (from 17 to 70 years) and 12 groups based on the downhill gradient they had covered over the last month (from 1,000 to 40,000 m). Results: Six hundred twenty-one questionnaires were collected from 45% of the participants in the seven races. Multivariate analysis revealed that self-reported KOOS scores were unrelated to age, sex and monthly downhill gradient. Only 74 (12%) of the participants reported previous knee injuries. Significant differences in the five subscales of the KOOS were found between skyrunners with and without previous knee injuries (P<0.01). Conclusions: In the studied population, regular training for downhill running and participation in Skyraces could not be considered risk factors for subjective knee symptoms. Skyrunners with selfreported histories of knee injuries scored worse on all five subscales of the KOO

Integrated Application of Active Controls (IAAC) technology to an advanced subsonic transpot project-demonstration act system definition

The 1985 ACT airplane is the Final Active Controls Technology (ACT) Airplane with the addition of three-axis fly by wire. Thus it retains all the efficiency features of the full ACT system plus the weight and cost savings accruing from deletion of the mechanical control system. The control system implements the full IAAC spectrum of active controls except flutter-mode control, judged essentially nonbeneficial, and incorporates new control surfaces called flaperons to make the most of wing-load alleviation. This redundant electronic system is conservatively designed to preserve the extreme reliability required of crucial short-period pitch augmentation, which provides more than half of the fuel savings

Spectral algorithms for reaction-diffusion equations

A collection of codes (in MATLAB & Fortran 77), and examples, for solving reaction-diffusion equations in one and two space dimensions is presented. In areas of the mathematical community spectral methods are used to remove the stiffness associated with the diffusive terms in a reaction-diffusion model allowing explicit high order timestepping to be used. This is particularly valuable for two (and higher) space dimension problems. Our aim here is to provide codes, together with examples, to allow practioners to easily utilize, understand and implement these ideas; we incorporate recent theoretical advances such as exponential time differencing methods and provide timings and error comparisons with other more standard approaches. The examples are chosen from the literature to illustrate points and queries that naturally arise